DIAKWANT^® · DIGITAL ASSAY · BREAST

DiaKwant^® HER2in breast

Use cell-level measurements of membrane intensity and completeness to support your review of the HER2 score.

CE MARKED UNDER IVDR, CLASS C, IN THE EUResearch Use Only outside the EU

HOW IT WORKS

From slide
to reviewable score.

The same three steps apply to every DiaKwant^® assay; the analysis in the middle is specific to the biomarker.

INPUT

Whole-slide image

Access the slide for quantification directly through your supported image management system.

ANALYSIS · BREAST

HER2

Use cell-level measurements of membrane intensity and completeness to support your review of the HER2 score.

REVIEW

Reviewable quantification result

The assay returns the score and supporting counts alongside the heatmap for expert review, following the ASCO or GEFPICS scoring guidelines configured for your laboratory.

AVAILABLE ON

PUBLICATIONS AND ABSTRACTS

Evidence for HER2.

Studies and congress abstracts listing HER2 as a biomarker. The full list is on the Resources page.

All publications ↗︎

USCAP · 2026

Impact of DiaKwant HER2 (DiaDeep) Artificial Intelligence (AI) Algorithm in the Evaluation of HER2-Low and HER2-Ultralow Status in Breast Cancer: Data from a Prospective Ring Trial in Greece

HER2 0+, according to CAP HER2 evaluation, or ultralow (UL) expression, is introduced in the assessment of HER2 status in advanced breast cancer (BC), to…

Entrainement et évaluation d'un algorithme d'IA de score HER2 : apport pour le pathologiste et l'oncologue

Une évaluation précise du statut HER2 est cruciale dans la prise de décision clinique. De plus, il a été démontré que les scores 1+ et 2+ non amplifiés et…

Training and evaluation of an AI-assisted HER2 scoring in breast carcinoma-stained whole-slide images

HER2 gene amplification occurs in 15% of invasive breast carcinomas. Given the exclusive effectiveness of HER2-targeted therapy in…

Practical
questions.

Practical information about HER2 scoring with DiaKwant^®.

What does DiaKwant HER2 report?

DiaKwant HER2 reports an IHC score in one of four categories: 0, 1+, 2+ or 3+.

Which tissue type is covered?

The assay covers breast carcinoma IHC whole-slide images.

Which scoring guidelines can be configured?

DiaKwant HER2 can be configured to the ASCO or GEFPICS scoring guidelines, depending on your laboratory's validated setup.

What can the pathologist review?

The pathologist can review a heatmap of membrane intensity and completeness, together with the reported result, before signing it off.

Does DiaKwant replace the pathologist?

No. DiaKwant is a diagnostic aid. The result must be reviewed by a qualified pathologist, who retains full responsibility for the final interpretation and report.

How can a laboratory confirm compatibility?

Technical compatibility depends on your laboratory's scanner and image management configuration. Contact the DiaDeep team to confirm compatibility for your validated setup.

CLUB QUANTI

See how DiaKwant^® handles the cases you encounter in your practice.

Compare its findings with your own scoring on your slides.

Try it on your cases ↗︎Apply to Club Quanti ↗︎