DIAKWANT^® · DIGITAL ASSAY · BREAST

DiaKwant^® ER / PRin breast

Interpretable nuclear positivity scores.

CE MARKED UNDER IVDR, CLASS C, IN THE EUResearch Use Only outside the EU

HOW IT WORKS

From slide
to reviewable score.

The same three steps apply to every DiaKwant^® assay; the analysis in the middle is specific to the biomarker.

INPUT

Whole-slide image

Access the slide for quantification directly through your supported image management system.

ANALYSIS · BREAST

ER / PR

Interpretable nuclear positivity scores.

REVIEW

Reviewable quantification result

The assay returns the score and supporting counts alongside the heatmap for expert review.

AVAILABLE ON

PUBLICATIONS AND ABSTRACTS

Evidence for ER / PR.

Studies and congress abstracts listing ER / PR as a biomarker. The full list is on the Resources page.

All publications ↗︎

ECP Dublin · 2023

End-to-end deep neural network for ER, PR and Ki-67 stained WSI automatic proliferation index (PI) quantification for breast cancer tissue

We develop an end-to-end pipeline based on a deep neural network for the quantification and assessment of nuclear biomarkers on stained WSI, i.e. ER, PR and…

End-to-End Deep Neural Network for Ki-67 Stained WSI Automatic Hotspot Detection and Proliferation Index (PI) Quantification for Breast Cancer Tissue

The advent of digitalisation of pathological laboratories and recent progress in artificial intelligence-driven computer vision emphasized the development of…

Practical
questions.

Practical information about ER / PR scoring with DiaKwant^®.

What does DiaKwant ER/PR quantify?

DiaKwant ER/PR quantifies the percentage of positive tumor nuclei on breast carcinoma IHC whole-slide images.

Are ER and PR reported separately?

Yes. ER and PR are analyzed and reported separately.

Which tissue type is covered?

The assay covers breast carcinoma IHC whole-slide images.

What information can the pathologist review?

A heatmap contextualizes the distribution of positive nuclei across the invasive tumor areas, for the pathologist to review.

Does DiaKwant replace the pathologist?

No. DiaKwant is a diagnostic aid. The result must be reviewed by a qualified pathologist, who retains full responsibility for the final interpretation and report.

How can a laboratory confirm compatibility?

Technical compatibility depends on your laboratory's scanner and image management configuration. Contact the DiaDeep team to confirm compatibility for your validated setup.

CLUB QUANTI

See how DiaKwant^® handles the cases you encounter in your practice.

Compare its findings with your own scoring on your slides.

Try it on your cases ↗︎Apply to Club Quanti ↗︎